I Am Not Entirely Sure Why Would You Use TWO Sans Serif Together In A Webpage

—namely, Helvetica and Lucida Grande/Sans (one for the headline and the other for the copy)—but I’ve seen lots of examples.

The best one? Even FontShop has done it, featuring not just two but THREE different sans.

“Just the usual: do what you’re good at and avoid what you’re not good at. Don’t talk about stuff you do not know about. Even harmless clients will have a bullshit detector and know when you’re out of your depths. Travel and learn. And ask whenever you don’t know something. It is my greatest fear to die stupid.”

Erik Spiekermann answered this tough question and more on ideasonideas.